Nonolfactory surface epithelium of the nasal cavity of the bonnet monkey: a morphologic and morphometric study of the transitional and respiratory epithelium.
Nonolfactory surface epithelium of the nasal cavity of the bonnet monkey: a morphologic and morphometric study of the transitional and respiratory epithelium.
复制标题
帽猴鼻腔的非嗅觉表面上皮：移行上皮和呼吸道上皮的形态学和形态测量研究。
DOI：
10.1002/aja.1001800308
复制
发表时间：
1987
期刊：
影响因子：
--
通讯作者：
Wong,VJ
中科院分区：
文献类型：
--
作者：
Harkema,JR;Plopper,CG;Hyde,DM;Wilson,DW;StGeorge,JA;Wong,VJ
本研究的目的是从超微结构上表征非人类灵长类动物（帽猴）的非嗅觉鼻上皮。对八只亚成年帽猴的鼻腔进行光学显微镜、扫描和透射电子显微镜检查。非嗅觉上皮覆盖了鼻腔的大部分，由鳞状上皮（SE）、移行上皮（TE）和呼吸道上皮（RE）组成。分层SE覆盖鼻前庭的鼻中隔和侧壁，而纤毛假复层RE覆盖大部分剩余鼻腔。前鼻腔 SE 和 RE 之间存在分层、无纤毛 TE。这种上皮在细胞数量和类型上与其他上皮群体不同。 TE由管腔无纤毛立方细胞、杯状细胞、小粘液颗粒（SMG）细胞和基底细胞组成，而RE包含纤毛细胞、杯状细胞、SMG细胞、基底细胞以及胞浆内排列有纤毛和微绒毛的细胞。 TE 和 RE 每毫米基底层含有相似数量的上皮细胞和基底细胞总数。与 RE 相比，TE 由更多的 SMG 细胞组成，但杯状细胞更少。我们得出的结论是，帽猴的非嗅觉鼻上皮非常复杂，具有不同的区域上皮群体，在充分评估该组织内的病理变化之前必须识别这些上皮群体。
The purpose of the present study was to characterize ultrastructurally the nonolfactory nasal epithelium of a nonhuman primate, the bonnet monkey. Nasal cavities from eight subadult bonnet monkeys were processed for light microscopy, and scanning and transmission electron microscopy. Nonolfactory epithelium covered the majority of the nasal cavity and consisted of squamous (SE), transitional (TE), and respiratory epithelium (RE). Stratified SE covered septal and lateral walls of the nasal vestibule, while ciliated pseudostratified RE covered most of the remaining nasal cavity. Stratified, nonciliated TE was present betwen SE and RE in the anterior nasal cavity. This epithelium was distinct from the other epithelial populations in abundance and types of cells present. TE was composed of lumenal nonciliated cuboidal cells, goblet cells, small mucous granule (SMG) cells, and basal cells, while RE contained ciliated cells, goblet cells, SMG cells, basal cells, and cells with intracytoplasmic lumina lined by cilia and microvilli. TE and RE contained similar numbers of total epithelial cells and basal cells per millimeter of basal lamina. TE was composed of more SMG cells but fewer goblet cells compared to RE. We conclude that nonolfactory nasal epithelium in the bonnet monkey is complex with distinct regional epithelial populations which must be recognized before pathologic changes within this tissue can be assessed adequately.