Antigliadin antibodies associated with chronic mucocutaneous candidiasis
Antigliadin antibodies associated with chronic mucocutaneous candidiasis
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DOI：
10.1046/j.1525-1470.2002.00117.x
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发表时间：
2002-09-01
影响因子：
1.5
通讯作者：
Oliva, NP
中科院分区：
文献类型：
--
作者：
Garcia, YH;Díez, SG;Oliva, NP
Chronic mucocutaneous candidiasis (CMC) is a primary immunodeficiency disease clinically characterized by Candida infection of the skin, mucous membranes, or nails that is refractory to traditional treatment. We present a typical case of a 13-year-old boy with an onset of illness at 1 month of age in the form of oral thrush. At age 2-3 years the patient began to have external otitis caused by Candida albicans and recurrent upper respiratory tract infections. Analytical studies detected iron deficiency and circulating antigliadin antibodies. Immunologic findings excluded other possible immunodeficiencies. Significant clinical improvement was produced by therapy with orally administered fluconazole. The significance of antigliadin antibodies is discussed.
