IS BLOOD-PRESSURE AN IMPORTANT VARIABLE IN RESEARCH ON AGING AND NEUROPSYCHOLOGICAL TEST-PERFORMANCE
IS BLOOD-PRESSURE AN IMPORTANT VARIABLE IN RESEARCH ON AGING AND NEUROPSYCHOLOGICAL TEST-PERFORMANCE
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DOI：
10.1093/geronj/45.4.p128
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发表时间：
1990-07-01
期刊：
影响因子：
--
通讯作者：
PIERCE, TW
中科院分区：
文献类型：
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作者：
ELIAS, MF;ROBBINS, MA;PIERCE, TW
使用血压、年龄以及血压和年龄的乘法效应作为表现的预测因子（在Halstead-Reitan神经心理测试组的选定测试中）进行回归分析。对年龄在20岁至72岁之间的受试者进行了三个假设的检验：(1)血压值在高血压和正常血压值的广泛范围内预测神经心理测试的表现；(2)血压在正常值和临界值的较窄范围内预测表现；(3)血压。年龄的相互作用，当观察到这个年龄和教育范围，是这样的负血压对表现的影响，年轻人比老年人更大。回归分析证实了这些假设，并表明当参与者没有高血压相关并发症和药物测试时，预测的强度并没有降低。血压。乘以。在初始样本中，年龄对trail - making- b测试和触觉性能测试（Tactile Performance Test- localization）存在交互作用。然而，当控制年龄、性别和教育程度时，仅观察到血压对平均损害等级、类别测试、tpt -记忆和tpt -定位的主要影响。本文讨论了这些发现对血压在衰老研究中的作用以及对不需要抗高血压药物治疗的受试者进行纵向研究的意义。
Regression analyses using Blood Pressure, Age, and the multiplicative effect of Blood Pressure and Age as predictors of performance (on selected tests from the Halstead-Reitan neuropsychological test battery) were done. Three hypotheses were tested with subjects ranging in age from 20 to 72 years of age: (1) blood pressure values predict neuropsychological test performance over a wide range of hypertensive and normotensive blood pressure values; (2) blood pressure predicts performance within the narrower range of normal and borderline values; (3) blood pressure .times. age interactions, when observed over this age and education range, are such that negative blood pressure effects on performance are larger for younger than older subjects. Regression analyses confirmed each of these hypotheses and indicated that strength of prediction was not reduced when participants free from hypertension-related complications and medication were tested. Blood pressure .times. age interactions were seen for Trailmaking-B Test and the Tactile Performance Test-Localization for the primary sample. However, only Blood Pressure main effects were observed for the Average Impairment Rating, the Categories Test, TPT-Memory and TPT-Localization when age, sex, and education were controlled. Implications of these findings for the role of blood pressure in aging research and for longitudinal studies with subjects free from the need for treatment with antihypertensive medications are discussed.