Negative Frequency-Dependent Selection Is Frequently Confounding
Negative Frequency-Dependent Selection Is Frequently Confounding
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DOI：
10.3389/fevo.2018.00010
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发表时间：
2018-02-21
影响因子：
3
通讯作者：
Brisson, Dustin
中科院分区：
文献类型：
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作者：
Brisson, Dustin
由于自然选择和遗传漂变倾向于侵蚀遗传多样性，种群内持续的遗传变异提出了一个进化问题。平衡选择模型的发展是为了解释在自然种群中观察到的遗传变异的维持。负频率依赖选择是一种强大的平衡选择类型，它维持了许多自然多态性，但它也经常被误解。本综述旨在阐明负频率依赖选择背后的过程，描述可能或不可能由这些过程产生的多态性类别，并讨论准确识别产生或维持自然多样性的过程所需的经验数据。最后，考虑到准确描述影响种群内遗传多样性过程的重要性，因为它与研究进展有关。
Persistent genetic variation within populations presents an evolutionary problem, as natural selection and genetic drift tend to erode genetic diversity. Models of balancing selection were developed to account for the maintenance of genetic variation observed in natural populations. Negative frequency-dependent selection is a powerful type of balancing selection that maintains many natural polymorphisms, but it is also commonly misinterpreted. This review aims to clarify the processes underlying negative frequency-dependent selection, describe classes of polymorphisms that can and cannot result from these processes, and discuss the empirical data needed to accurately identify processes that generate or maintain diversity in nature. Finally, the importance of accurately describing the processes affecting genetic diversity within populations as it relates to research progress is considered.