Neuropsychiatric Syndromes in Neurodegenerative Disease: Frequency and Signficance.
Neuropsychiatric Syndromes in Neurodegenerative Disease: Frequency and Signficance.
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DOI：
10.1053/scnp00100241
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发表时间：
1996-10
期刊：
影响因子：
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通讯作者：
Jeffrey L. Cummings;C. Diaz;M. Levy;G. Binetti;I. LitvanI
中科院分区：
文献类型：
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作者：
Jeffrey L. Cummings;C. Diaz;M. Levy;G. Binetti;I. LitvanI
神经退行性疾病具有神经心理学、神经精神病学和神经学效应，表现为认知、情感和身体改变。这些主要影响对日常生活活动、患者和护理人员的痛苦以及生活质量产生了次要影响。神经精神表现是大脑功能障碍的产物，与机构化、易受照顾者虐待以及使用药物和限制有关。行为改变通常可以通过精神药物来改善，药物的作用有助于理解行为改变的机制。痴呆症患者的卫生服务资源的分配部分取决于这些疾病的神经精神方面，变性疾病的神经精神方面的重要性一直没有得到充分强调。
Neurodegenerative diseases have neuropsychological, neuropsychiatric, and neurological effects manifested as cognitive, emotional, and physical alterations. These primary effects have secondary consequences on activities of daily living, patient and caregiver distress, and quality of life. Neuropsychiatric manifestations are products of brain dysfunction that are associated with institutionalization, vulnerability to abuse by the caregiver, and use of medications and restraints. Behavioral alterations can often be ameliorated by psychotropic drugs, and the effects of medications contribute to understanding the mechanisms of behavioral changes. Allocation of health service resources for dementia patients is partially determined by the neuropsychiatric dimension of these diseases, and the importance of the neuropsychiatric aspects of degenerative disorders has been underemphasized.