Validation of right and left ventricular conductance and echocardiography for cardiac function studies
Validation of right and left ventricular conductance and echocardiography for cardiac function studies
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DOI：
10.1016/0003-4975(96)00377-3
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发表时间：
1996-10-01
影响因子：
4.6
通讯作者：
Spotnitz, HM
中科院分区：
文献类型：
--
作者：
Amirhamzeh, MMR;Dean, DA;Spotnitz, HM
背景。从瞬时电导连续估计左心室容积与“黄金标准”相比毫不逊色，劳动密集度较低，并且提供实时数据。然而，将右心室电导与此类黄金标准相关联或检查对侧心室中产生的电场的影响的信息很少。方法。在开胸绵羊中，在稳态条件下测量右心室和左心室电导、二维超声心动图和热稀释心输出量。在这些测量之后，进行死后压力-容积关系、心室质量和心室铸型。结果。通过电导测量的校正舒张末期容积与通过超声心动图（r = 0.89）、死后压力-容积关系（r = 0.84）和铸型（r = 0.85）测量的容积良好相关。通过方差分析，通过电导测量的左心室舒张末期容积与其他标准没有显着差异。对侧心室中电场的存在不会影响所研究心室中测量的电导。结论。电导可用于测量跳动心脏中的右心室和左心室舒张末期容积，并且不受对侧心室中存在电场的影响。因此，电导在涉及心室依赖性和功能的研究中是一个有用的工具。
Background. Continuous estimation of left ventricular volume from instantaneous conductance has compared favorably with ''gold standards,'' is less labor intensive, and provides real-time data. Little information exists, however, correlating right ventricular conductance with such gold standards or examining the effects of an electrical field generated in the opposite ventricle.Methods. In open-chested sheep, right and left ventricular conductance, two-dimensional echocardiography, and thermodilution cardiac outputs were measured at steady-state conditions. After these measurements, postmortem pressure-volume relations, ventricular mass, and ventricular casting were performed.Results. The corrected end-diastolic volume measured by conductance correlated well with volumes measured by echocardiography (r = 0.89), postmortem pressure-volume relations (r = 0.84), and casts (r = 0.85). Left ventricular end-diastolic volume measured by conductance did not differ significantly from other standards by analysis of variance. The presence of an electrical field in the opposite ventricle did not affect measured conductance in the studied ventricle.Conclusions. Conductance is useful for the measurement of right and left ventricular end-diastolic volumes in the beating heart and is not affected by the presence of an electrical field in the opposite ventricle. Hence, conductance is a useful tool in studies involving interventricular dependence and function.