Three dimensional ultrasound of retinoblastoma: initial experience

Three dimensional ultrasound of retinoblastoma: initial experience
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DOI:
10.1136/bjo.86.10.1136
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发表时间:
2002-10-01
影响因子:
4.1
通讯作者:
Garcia, JPS
Garcia, JPS
中科院分区:
医学2区
文献类型:
--
作者:
Finger, PT;Khoobehi, A;Garcia, JPS

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目的:目的:应用三维超声(3DUS)诊断视网膜母细胞瘤(retinoblastoma,RB),方法:采用市售的计算机三维超声系统,对3例5眼视网膜母细胞瘤患儿的三维图像进行存储和重建。结果:3DUS检查显示视网膜母细胞瘤的特征:内生性肿块、视网膜脱离、瘤内钙化和继发性眼眶阴影。与2D成像不同,3DUS可用于分析获得和储存的体积。旋转和切片的体积允许新的斜和冠状面视图的发现,例如,钙相关的眼眶阴影被视为3D卷和(冠状面)视神经的横截面进行了评价,为证据的神经内入侵的视网膜母细胞瘤。结论:这是第一次报道的一系列患者检查与3DUS成像视网膜母细胞瘤。该技术允许肿瘤和视神经的新的斜位和冠状位视图,回顾性分析(扫描和存储的)眼球体积的能力促进了患者护理、教学、肿瘤体积分析和远程医疗。
Aim: To use 3D ultrasonography (3DUS) for the diagnosis of retinoblastoma.Methods: Five eyes of three children with retinoblastoma were evaluated using a commercially available computerised 3DUS system, Interactive sectioning of the stored and reconstructed 3D volumes were performed. 3DUS and histopathological findings were correlated after enucleation.Results: 3DUS examination revealed characteristics consistent with retinoblastoma: endophytic mass, retinal detachment, intratumoural calcifications, and secondary orbital shadowing, Unlike 2D imaging, 3DUS allowed for analysis of the acquired and stored volumes. Rotation and sectioning of this volume allowed the discovery of new oblique and coronal views, For example, calcium related orbital shadows were seen as 3D volumes and (coronal) cross sections of the optic nerve were evaluated for evidence of intraneural invasion by retinoblastoma.Conclusion: This is the first reported series of patients examined with 3DUS imaging for retinoblastoma. This technique allowed for new oblique and coronal views of the tumour and optic nerve, The ability to retrospectively analyse the (scanned and stored) ocular volume facilitated patient care, teaching, tumour-volume analysis, and telemedicine.