Subperiosteal abscess of the orbit. Age as a factor in the bacteriology and response to treatment.
Subperiosteal abscess of the orbit. Age as a factor in the bacteriology and response to treatment.
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眼眶骨膜下脓肿。
DOI：
10.1016/s0161-6420(94)31297-8
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发表时间：
1994
期刊：
影响因子：
13.7
通讯作者：
Harris,GJ
中科院分区：
文献类型：
--
作者：
Harris,GJ
背景：早期对继发于鼻窦炎的骨膜下脓肿的研究表明，在临床病程和细菌学方面有相当大的差异。在一个极端，患者仅用静脉注射抗生素就能康复；在另一个极端，尽管早期手术引流和适当的抗生素，复杂的病原体仍然存在，并出现视觉或颅内并发症。为了更好地指导患者的治疗，本研究评估了患者年龄在骨膜下脓肿复杂性和反应性中的作用。方法：回顾37例骨膜下脓肿的CT诊断。最初和后续培养结果是在个体患者先前治疗的背景下进行评估的。结果：在9岁以下的患者中，83%的患者在没有引流的情况下清除了细菌(25%)，或者在引流时培养阴性(58%)。在培养阳性的病例中，仅发现单一需氧菌，未分离出厌氧菌。9至14岁的患者表现出向更复杂的感染的过渡。15岁或15岁以上的患者在使用抗生素超过3天后均有阳性培养，这在体外通常是有效的。结论：骨膜下脓肿的复杂性和反应性的差异似乎与年龄有关。治疗方案应考虑视力损害、疼痛、脓肿的位置、受累的鼻窦、颅内并发症和患者的年龄。
Background:Earlier studies of subperiosteal abscess secondary to sinusitis showed considerable variation in the clinical course and bacteriology. At one extreme, patients recovered with intravenous antibiotics alone; at the other extreme, complex pathogens persisted despite early surgical drainage and appropriate antibiotics, and visual or intracranial complications occurred. To better direct management of individual patients, this study evaluates the role of patient age in the complexity and responsiveness of subperiosteal abscess.Methods:The records of 37 patients with a computed tomography diagnosis of subperiosteal abscess were reviewed. Initial and follow-up culture results were evaluated in the context of prior treatment of individual patients. Responses to therapy and pathogens were compared among three age groups.Results:Among patients younger than 9 years, 83% either cleared without drainage (25%) or had negative cultures at the time of drainage (58%). In the culture-positive cases, single aerobes were found, and anaerobes were not isolated. Patients 9 to 14 years old showed a transition toward more complex infections. Patients 15 years of age or older all had positive cultures after more than 3 days of antibiotics, which were frequently effective in vitro. Polymicrobial infections were the rule, including anaerobes in every case.Conclusion:Variations in the complexity and responsiveness of subperiosteal abscesses appear to be age-associated. Treatment protocols should consider visual compromise, pain, location of the abscess, which sinuses are involved, intracranial complications, and the age of the patient.
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眼眶脓肿的医疗治疗。
影响因子：
5.1
作者：
M. Tanenbaum;J. Tenzell;S. F. Byrne;R. Forster
通讯作者：
R. Forster
儿童眼眶骨膜下脓肿的医疗治疗。
影响因子：
1.2
作者：
S. Rubin;Rubin Lg;J. Zito;Goldstein Mn;C. Eng
通讯作者：
C. Eng
影响因子：
--
作者：
G. Harris
通讯作者：
G. Harris
DOI：
10.1288/00005537-198103000-00004
发表时间：
1981
期刊：
The Laryngoscope
影响因子：
--
作者：
I. Brook
通讯作者：
I. Brook
急性鼻窦炎的眼眶受累
影响因子：
1.6
作者：
D. B. Hawkins;R. W. Clark
通讯作者：
R. W. Clark