Development of chemically modified oligonucleotide therapeutics and mechanistic probes
Development of chemically modified oligonucleotide therapeutics and mechanistic probes
批准号:
170617
负责人:
Damha Masad J
金额:
$25.5万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2008
资助国家:
加拿大
项目状态:
已结题
起止时间:
2008-09-01 至 2011-09-01
中文摘要
RNA干扰(RNAi)是一种自然的细胞机制,通过靶向的mRNA降解选择性地沉默基因的表达,防止基因编码蛋白的产生。激活RNAi途径的合成寡核苷酸(ON)具有模板
英文摘要
RNA interference (RNAi) is a natural cellular mechanism for selectively silencing the expression of genes via targeted mRNA degradation, preventing gene-coded protein production. Synthetic oligonucleotides (ONs) that activate the RNAi pathway have tremen
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会议论文
Modifying Gene Expression with Synthetic Nucleic Acid Therapeutics
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批准号:239159
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项目类别:Operating Grants
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资助金额:$25.43万
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财政年份:2011
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负责人:Damha Masad J
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依托单位:
海外基金