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Regulation of EGFR-mediated Cell Signaling and Endocytosis during Mitosis

Regulation of EGFR-mediated Cell Signaling and Endocytosis during Mitosis
有丝分裂过程中 EGFR 介导的细胞信号传导和内吞作用的调节
批准号:
215438
负责人:
Wang Zhixiang
金额:
$47.39万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2010
资助国家:
加拿大
项目状态:
已结题
起止时间:
2010-09-01 至 2015-09-01

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中文摘要
翻译
细胞的生长受各种生长因子的控制。生长因子与细胞表面的受体结合,通过激活这些受体来刺激细胞生长。这些受体的过度激活会导致细胞过度生长,导致癌症
英文摘要
Cell growth is controlled by various growth factors. Growth factors bind to their receptors at cell surface to stimulate cell growth by activating these receptors. Over-activation of these receptors will cause the over-growth of the cells, leading to canc
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会议论文
Novel function of Rac1 in nuclear speckle, its regulation and implication in breast cancer
  • 批准号:
    472376
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2022
  • 负责人:
    Wang Zhixiang
  • 依托单位:
Rac1 phosphorylation: A novel mechanism to regulate Rac1 activity and function
  • 批准号:
    342642
  • 项目类别:
    Operating Grants
  • 资助金额:
    $31.47万
  • 财政年份:
    2016
  • 负责人:
    Wang Zhixiang
  • 依托单位:
海外基金