Role of progranulin in the TDP-43/FUS pathway in Amyotrophic Lateral Sclerosis (ALS) pathogenesis
Role of progranulin in the TDP-43/FUS pathway in Amyotrophic Lateral Sclerosis (ALS) pathogenesis
批准号:
226522
负责人:
Aroonassala Patten Shunmoogum
金额:
$6.56万
依托单位:
依托单位国家:
加拿大
项目类别:
Fellowship Programs
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-02-01 至 2013-02-01
中文摘要
了解肌萎缩侧索硬化症(ALS)相关基因(PGRN、TDP-43、FUS)的作用。我将研究PGRN的作用及其与TDP-43和FUS的遗传相互作用,这两种基因最近被认为与ALS有关。试析PGRN的作用
英文摘要
To understand the role of genes (PGRN, TDP-43, FUS) linked to amyotrophic lateral sclerosis (ALS). I will investigate the role of the PGRN and its genetic interaction with TDP-43 and FUS which have recently been linked to ALS. Analysis of the role of PGRN
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