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Function of the BTB/POZ domain transcription factor Miz-1 in the activation of lymphoid cells and in lymphoid leukemia and lymphoma

Function of the BTB/POZ domain transcription factor Miz-1 in the activation of lymphoid cells and in lymphoid leukemia and lymphoma
BTB/POZ 结构域转录因子 Miz-1 在淋巴细胞活化以及淋巴白血病和淋巴瘤中的功能
批准号:
224822
负责人:
Moroy Tarik
金额:
$51.47万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-03-01 至 2016-03-01

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中文摘要
翻译
淋巴瘤和白血病都是血细胞、血细胞前体甚至是血液干细胞的癌症,这些细胞被编程形成血细胞。淋巴瘤是指位于淋巴结、脾或胸腺的实体肿块,而白血病的特征是
英文摘要
Lymphoma and leukemia are both cancers of blood cells, blood cell precursors or even blood stem cells that are programmed to form blood cells. While a lymphoma is present as a solid tumor mass in lymph nodes, spleen or thymus, leukemia is characterized by
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The MYC/MIZ-1 complex in germinal center B cells and B cell lymphomagenesis
Therapeutic potential of the long non-coding RNA ELDR for the Acute Myeloid Leukemia subtype M5 with t(9;11) translocations
The role of the RNA helicase DDX3X in Burkitt Lymphoma and its potential as a new therapeutic target
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