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Regulation of TGF-beta action in chondrocytes: Role of ALK1-endoglin interplay

Regulation of TGF-beta action in chondrocytes: Role of ALK1-endoglin interplay
软骨细胞中 TGF-β 作用的调节：ALK1-内皮糖蛋白相互作用的作用
批准号：
225735
负责人：
Philip Anie
金额：
$18.47万
依托单位：
Research Institute of the McGill University Health Centre
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2011
资助国家：
加拿大
项目状态：
已结题
起止时间：
2011-03-01 至 2014-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=225735&lang=en
关键词：
Alk1 Animal Model Arthritis Cartilage Cartilage Regeneration Chondrocytes Endoglin Osteoarthritis Receptors Tgf-Beta

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中文摘要
翻译
关节炎是一种严重的医学问题，影响着绝大多数人，治疗方法有限。疼痛、关节炎症和肿胀等症状对关节活动有不利影响，对关节质量有重大影响
英文摘要
Arthritis is a serious medical problem affecting a large majority of the population and has limited options for treatment. Symptoms including pain, joint inflammation and swelling have adverse effects on joint mobility and a significant impact on quality
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Regulation of TGF-beta action in chondrocytes: signaling via ALK1 versus ALK5 pathways
Regulation of TGF-beta action in chondrocytes: signaling via ALK1 versus ALK5 pathways
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