PET and SPECT Probes for the Diagnosis of Alzheimer's Disease Targeting Cholinesterase Activity
PET and SPECT Probes for the Diagnosis of Alzheimer's Disease Targeting Cholinesterase Activity
批准号:
354430
负责人:
Darvesh Sultan
金额:
$106.17万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-10-01 至 2021-10-01
中文摘要
胆碱酯酶是一种参与分解乙酰胆碱的酶,乙酰胆碱是一种神经递质,在脑细胞通讯中很重要,在阿尔茨海默病(AD)中减少。阿尔茨海默病的特点是记忆丧失和对胸罩有毒的异常蛋白质的沉积
英文摘要
Cholinesterases are enzymes involved in the breakdown of acetylcholine, a neurotransmitter, important in brain cell communication, that is reduced in Alzheimer's disease (AD). AD is marked by loss of memory and deposition of abnormal proteins toxic to bra
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依托单位:
海外基金