课题基金 / 基金详情

Determining The Molecular Mechanisms of Cell-Cell Fusion in Muscle Development and Regeneration

Determining The Molecular Mechanisms of Cell-Cell Fusion in Muscle Development and Regeneration
确定肌肉发育和再生中细胞与细胞融合的分子机制
批准号：
404188
负责人：
Zhang Yichi
金额：
$7.65万
依托单位：
University of Texas Southwestern Medical Center
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2018
资助国家：
加拿大
项目状态：
已结题
起止时间：
2018-10-01 至 2021-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=404188&lang=en
关键词：
Cell Fusion Crispr Loss-Of-Function Screening Crispr-Cas9 Development High Resolution Confocal Microscopy Knockout Mice Muscle Injury Regeneration Tandem Affinity Purification Time-Lapse Imaging

项目摘要

项目成果

相关文献

中文摘要
翻译
骨骼肌的形成需要肌肉细胞相互融合，并与现有肌肉融合，形成成熟的肌纤维。我们实验室最近发现了两种定位于细胞的蛋白质
英文摘要
The formation of skeletal muscle during development and following muscle injury requires muscle cells to fuse with each other and with existing muscle to form mature muscle fibers. Our laboratory has recently discovered two proteins localized to the cell
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