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An epigenetic "inflammaging" score (EIS) as a tool to quantify healthy aging and predict adverse health outcomes in older adults

An epigenetic "inflammaging" score (EIS) as a tool to quantify healthy aging and predict adverse health outcomes in older adults
表观遗传“炎症”评分(EIS)作为量化健康老龄化和预测老年人不良健康结果的工具
批准号:
408706
负责人:
Verschoor Chris P
金额:
$5.1万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-09-01 至 2020-09-01

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中文摘要
翻译
随着年龄的增长,体内通常与炎症相关的细胞和分子水平会增加。这种现象被称为“发炎”,这是每个人身上都会发生的自然过程,尽管对于那些随着年龄增长而健康状况不佳的人来说,发炎是一种自然的过程。
英文摘要
As we age, levels of cells and molecules commonly associated with inflammation increase in the body. This phenomenon, coined "inflammaging", is a natural process that occurs in everyone, although for those that are less healthy as they age, inflammaging c
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Exploring the breakdown of biological systems in older adults using high-dimensional metabolomic data
A comprehensive approach to quantifying chronic inflammation in older adults
Health-age: a composite biomarker measure to estimate healthy aging in older Canadians
  • 批准号:
    389201
  • 项目类别:
    Operating Grants
  • 资助金额:
    $0.0万
  • 财政年份:
    2018
  • 负责人:
    Verschoor Chris P
  • 依托单位:
Elevated serum cytokines (inflammaging) promotes a dysfunctional monocyte/macrophage response to S. pneumoniae in the elderly.
  • 批准号:
    269111
  • 项目类别:
  • 资助金额:
    $0.07万
  • 财政年份:
    2012
  • 负责人:
    Verschoor Chris P
  • 依托单位:
海外基金