Determine how the interaction between SARS-CoV-2 spike protein and angiotensin-converting enzyme 2 (ACE2) affect viral spread and the severity of COVID-19 outcomes.
Determine how the interaction between SARS-CoV-2 spike protein and angiotensin-converting enzyme 2 (ACE2) affect viral spread and the severity of COVID-19 outcomes.
批准号:
449017
负责人:
Su Ruey-Chyi
金额:
$31.4万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2021
资助国家:
加拿大
项目状态:
已结题
起止时间:
2021-04-01 至 2022-04-01
中文摘要
拟议的研究重点是调查为什么SARS-CoV-2变体B.1.1.7与宿主细胞上的血管紧张素转换酶2 (ACE2)具有更高的结合亲和力,与病毒传播和死亡率增加相关。ACE2,主要re
英文摘要
The proposed research focuses on investigating why the SARS-CoV-2 variant, B.1.1.7 that have higher binding affinity to Angiotensin Converting Enzyme 2 (ACE2) on host cells are associated with increased viral spread and mortality rates. ACE2, the main re
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会议论文
Elucidating the role of cell homing pathways in controlling endothelial cell-mediated enhancement of resting CD4+ T cell infection by HIV
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批准号:366806
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项目类别:Operating Grants
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资助金额:$15.05万
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财政年份:2017
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负责人:Su Ruey-Chyi
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依托单位:
海外基金