Function, Mechanism and Dynamics in Fluorescent Proteins: a Computational Investigation

大堡礁生态系统中丰富的色素蛋白和荧光蛋白为澳大利亚发展基于细胞生物学和生物医学成像荧光标记的生态位生物技术产业提供了独特的自然优势。这个项目为发展这样一个产业提供了一个至关重要的科学组成部分：一个关于这些蛋白质如何发挥作用的分子水平的知识，以及我们如何操纵和增强它们作为显像剂的特性。它将在生物分子建模技术方面取得基本进展，培养具有极其宝贵技能的毕业生，并获得有助于澳大利亚生物技术产业发展的知识。

The rich reservoir of chromoproteins and fluorescent proteins in the ecosystem of the Great Barrier Reef offers Australia a unique natural advantage for the development of a niche biotechnology industry based on fluorescent markers for cellular biology and biomedical imaging. This project provides a crucial component of the science that is necessary for developing such an industry: a molecular-level knowledge of how these proteins function and how we can manipulate and enhance their properties as imaging agents. It will achieve fundamental advances in biomolecular modelling techniques, train graduates with exceedingly valuable skill sets as well as deriving knowledge that aids the development of Australia's biotech industries.