Waking up Hepatitis B virus (HBV)'s chronic form to maximize attack by promoter-targeting therapies
Waking up Hepatitis B virus (HBV)'s chronic form to maximize attack by promoter-targeting therapies
批准号:
486942
负责人:
Kasinyabo Emmanuelle
金额:
$0.44万
依托单位:
依托单位国家:
加拿大
项目类别:
Miscellaneous Programs
财政年份:
2023
资助国家:
加拿大
项目状态:
已结题
起止时间:
2023-05-01 至 2023-09-01
中文摘要
简介:B肝炎病毒(HBV)由于其慢性形式的持续存在而保持慢性,共价闭合环状DNA(cccDNA)仍然隐藏在细胞核中,包裹在组蛋白周围,并且不被目前的治疗靶向。因此,在战略中
英文摘要
INTRO: Hepatitis B virus (HBV) remains chronic due to the persistence of its chronic form, the covalently closed circular DNA (cccDNA), which remains hidden in the nucleus, wrapped around histones and untargeted by current therapies. Thus, in the strategy
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