Molecular dissection of malaria parasite motility and host-cell invasion across the lifecycle
Molecular dissection of malaria parasite motility and host-cell invasion across the lifecycle
批准号:
FT100100112
负责人:
Prof Jake Baum
金额:
$35.18万
依托单位国家:
澳大利亚
项目类别:
ARC Future Fellowships
财政年份:
2011
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2011-01-01 至 2013-10-25
中文摘要
疟疾寄生虫以一种独特的方式移动,通过一种独特的分子马达在细胞表面滑动并感染宿主细胞。这项研究的目的是了解寄生虫运动背后的分子力学,并利用它来开发新的药物,这些药物可能会干扰寄生虫的运动,阻断它们的运动,从而预防疟疾。
英文摘要
Malaria parasites move in a unique way, gliding across cell surfaces and infecting host cells using a unique molecular motor. This research aims to understand the molecular mechanics behind parasite movement and use this to develop novel drugs that might throw a spanner in the parasite motor, blocking movement and thereby preventing malaria disease.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
The Evolution and Diversification of Apicomplexan Cell Invasion Mechanisms
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批准号:DP0559372
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项目类别:Discovery Projects
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资助金额:$0.0万
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财政年份:2005
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负责人:Prof Jake Baum
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依托单位:
海外基金