Novel approach for the drug delivery of L-asparaginase in the treatment of acute lymphoblastic leukemia
Novel approach for the drug delivery of L-asparaginase in the treatment of acute lymphoblastic leukemia
批准号:
367141
负责人:
gynn matthew D
金额:
$1.27万
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-12-01 至 2017-12-01
中文摘要
健康的细胞拥有一种叫做天冬酰胺合成酶的酶,它能产生氨基酸天冬酰胺,这是蛋白质合成和细胞存活所必需的。结果表明,大多数急性淋巴细胞白血病(ALL)细胞停止表达天冬酰胺合成酶
英文摘要
Healthy cells possess an enzyme called asparagine synthetase that generates the amino acid asparagine, which is necessary for protein synthesis and cell survival. Most of Acute Lymphoblastic Leukemia (ALL) cells stop expressing asparagine synthetase, resu
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