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Mucosal Associated Invariant T-cells (MAIT cells) as Key Mediators of Anti-Tumor Immune Responses and the Microbiome Effect in Non-Small Cell Lung Cancer (NSCLC)

Mucosal Associated Invariant T-cells (MAIT cells) as Key Mediators of Anti-Tumor Immune Responses and the Microbiome Effect in Non-Small Cell Lung Cancer (NSCLC)
粘膜相关不变 T 细胞 (MAIT 细胞) 作为非小细胞肺癌 (NSCLC) 抗肿瘤免疫反应和微生物组效应的关键介质
批准号:
409612
负责人:
Sacher Adrian G
金额:
$20.62万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-09-01 至 2022-09-01

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中文摘要
翻译
最近,免疫疗法如PD1抑制剂的发展使肺癌的治疗发生了革命性的变化。然而,由于对免疫细胞群的了解有限,开发改进免疫疗法的尝试受到了阻碍
英文摘要
The treatment of lung cancer has been recently revolutionized by the development of immunotherapies such as PD1 inhibitors. However, attempts to develop improved immunotherapies have been hampered by a limited understanding of the immune cell populations
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会议论文
Quantitative Plasma Genotyping as a Biomarker of Treatment Response in Advanced NSCLC
  • 批准号:
    318940
  • 项目类别:
    Fellowship Programs
  • 资助金额:
    $4.37万
  • 财政年份:
    2014
  • 负责人:
    Sacher Adrian G
  • 依托单位:
Translating targeted next-generation sequencing into a clinical tool for personalized management of squamous cell lung cancer
  • 批准号:
    302457
  • 项目类别:
    Fellowship Programs
  • 资助金额:
    $0.0万
  • 财政年份:
    2013
  • 负责人:
    Sacher Adrian G
  • 依托单位:
国内基金
海外基金
Autoimmune diseases therapies: variations on the microbiome in rheumatoid arthritis