Biosynthesis and Metabolism of Linoleic Acid in Insects

昆虫体内亚油酸的生物合成与代谢 首席研究员最近的工作提供了证据， 一些昆虫不像脊椎动物可以合成 多不饱和脂肪酸从头开始。 分离的实验 豌豆蚜虫、美洲蟑螂和蟋蟀的组织 应提供明确的证据，以排除参与 共生微生物在这些脂肪酸的合成。 关键酶将被表征和特异性底物 鉴定 这项研究的结果应该有助于我们 了解多不饱和脂肪酸的功能和代谢 昆虫中的脂肪酸 昆虫生物化学知识 特别是它与脊椎动物的不同之处， 有助于开发更安全的医疗管理方法， 重要的经济昆虫

Biosynthesis and Metabolism of Linoleic Acid in Insects: Recent work by the principal investigator presents evidence that some insects unlike vertebrates can synthesize polyunsaturated fatty acids de novo. Experiments with isolated tissues from pea aphids, American cockroaches and crickets should provide unambiquous evidence to rule out involvement of symbiotic microorganisms in the synthesis of these fatty acids. The key enzyme will be characterized and specific substrate identified. The results of this research should contribute to our understanding of the function and metabolism of polyunsaturated fatty acids in insects. Knowledge of insect biochemistry especially as it differs from that of vertebrates will be helpful in developing safer methods for managing medically and economically important insects.