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Acquisition of an Atomic Absorption Spectrophotometer and Furnace Atomizer

Acquisition of an Atomic Absorption Spectrophotometer and Furnace Atomizer
购置原子吸收分光光度计和炉原子化器
批准号:
8711103
负责人:
Carol Colton
金额:
$4.77万
依托单位:
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
1988
资助国家:
美国
项目状态:
已结题
起止时间:
1988-09-01 至 1991-02-28

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中文摘要
翻译
在三个不同的研究项目中,原子吸收光谱仪是超微量元素测量所必需的。它将被用来测定海马片中的金属含量(特别是锌和铁)。目的是探讨氧化应激过程中脑组织金属含量与神经元损伤的关系。另一个项目将使用该设备测量新生大鼠肾脏管状液纳升样本中的钠和钾浓度。这些测量将被用来评估心钠素在未成熟大鼠水和电解质平衡中的作用。对于第三个项目,原子吸收光谱仪还将用于测定肾小管液纳升样本中的钠和钾浓度。神经体液因素,特别是多巴胺,对新生大鼠钠排泄的调节作用将被检验。原子吸收光谱仪和石墨炉原子化器提供了独特的能力,可以以合理的成本测量极小的组织和液体样品中各种金属和离子的含量。
英文摘要
An atomic absorption spectrophotometer with furnace atomizer is essential for ultra-micro elemental measurements in three different research projects. It will be used to determine metal content (particularly zinc and iron) in hippocampal slices. The objective is to investigate the relationship of tissue metal content to neuronal damage in the brain during exposure to oxidative stress. Another project will use this equipment to measure sodium and potassium concentrations in nanoliter samples of tubular fluid from neonatal rat kidneys. The measurements will be used to assess the role of atrial natriuretic factor in water and electrolyte homeostasis in the immature rat. For the third project, the atomic absorption spectrophotometer will also be used to determine sodium and potassium concentrations in nanoliter samples of renal tubular fluid. The role of neurohumoral factors, particularly dopamine, regulation of sodium excretion in neonatal rats will be examined. The atomic absorption spectrophotometer and graphite furnace atomizer offers the unique capability of measuring the content of various metals and ions in extremely small samples of tissue and fluid at a reasonable cost.
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Action of Reactive Oxygen Intermediated on Synaptic Transmission
  • 批准号:
    8615846
  • 项目类别:
    Continuing Grant
  • 资助金额:
    $16.13万
  • 财政年份:
    1987
  • 负责人:
    Carol Colton
  • 依托单位:
海外基金