Mechanistic Organometallic Chemistry

这一奖项来自无机化学、生物无机化学和金属有机化学项目，是金属有机化学领域的奖项。该项目的重点是两个铁原子通过碳氢桥连接在一起的新化合物的反应机理。这类化合物是合成各种有机化合物的重要试剂，有关其反应机理的信息有望导致合成方法的改进。将探索新的二铁化合物与桥烃配体的反应性，并深入探讨这些化合物新反应的机理。预计这项研究将导致几个新的碳-碳键形成反应，在有机合成中具有潜在的用途。为了实现这一合成潜力，将探索从双铁络合物中裂解桥联碳氢基的方法。将研究金属卡宾配合物与烯烃反应中环丙烷的生成机理，并尝试在环丙化反应中生成所建议的中间体，以确定它们是否会导致环丙烷的生成。金属卡宾络合物的反应既不是强亲核的，也不是强亲电的，将被用来填补对金属卡宾络合物的一个重要的认识空白。

This award from the Inorganic, Bioinorganic and Organometallic Chemistry Program is in the area of organometallic chemistry. The focus of the project is the mechanisms of reactions of new compounds in which two iron atoms are held together by a hydrocarbon bridge. Such compounds are important reagents for the synthesis of a wide variety of organic compounds, and information about their reaction mechanisms is expected to lead to improvements in synthetic methodology. The reactivity of new diiron compounds with bridging hydrocarbon ligands will be explored, and the mechanisms of new reactions of these compounds will be explored in depth. It is anticipated that this study will lead to several new carbon-carbon bond forming reactions of potential use in organic synthesis. In order for this synthetic potential to be realized, ways of cleaving the bridging hydrocarbyl group from the diiron complex will be explored. The mechanism of cyclopropane formation in the reactions of metal-carbene complexes with alkenes will be studied, and an attempt will be made to generate the suggested intermediates in cycloproponation reactions to see if they lead to cyclopropanes. The reactions of metal carbene complexes which are neither strong nucleophiles nor strong electrophiles will be explored to fill an important gap in the understanding of metal-carbene complexes.