Improved Screening Methods for CCR5-Antagonists Use by Ultra Deep Sequencing and Quantitative Population-Based Sequencing Techniques: Analyzes of the Phase III Human Clinical Trials of Maraviroc (08-09).

HAART的终身性质和艾滋病毒迅速变异的能力引起了人们对治疗反应和毒性的决定因素以及耐药性的发展的关注。开发新型抗逆转录病毒非常重要

The life-long nature of HAART and the ability of HIV to mutate rapidly have led to concerns about the determinants of treatment response and toxicity, as well as the development of drug resistance. It is important to develop novel classes of antiretrovira