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Bortezomib mediated BRCAness in Myeloma cells: novel therapeutic approach combining PARP1-2 and 26S proteasome inhibitors.

Bortezomib mediated BRCAness in Myeloma cells: novel therapeutic approach combining PARP1-2 and 26S proteasome inhibitors.
硼替佐米介导骨髓瘤细胞中的 BRCA:结合 PARP1-2 和 26S 蛋白酶体抑制剂的新型治疗方法。
批准号:
248595
负责人:
Bahlis Nizar J
金额:
$0.0万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-09-01 至 2012-09-01

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中文摘要
翻译
多发性骨髓瘤是第二种最常见的血癌形式,尽管在治疗该疾病的治疗手段中加入了新的治疗药物,但仍然无法治愈。因此,蛋白酶体抑制剂硼替佐米具有显著的i
英文摘要
Multiple myeloma is the second most common form of blood cancers and remains incurable despite the addition of novel therapeutic agents to the treatment armamentarium for this disease. As such, while the proteasome inhibitor Bortezomib has significantly i
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Bortezomib mediated BRCAness in Myeloma cells: novel therapeutic approach combining PARP1-2 and 26S proteasome inhibitors.
  • 批准号:
    267173
  • 项目类别:
    Operating Grants
  • 资助金额:
    $38.09万
  • 财政年份:
    2012
  • 负责人:
    Bahlis Nizar J
  • 依托单位: