PI3K gamma is required for linkage between VLA-4 integrins and the actin cytoskeleton, a critical step for leukocyte recruitment from blood to extravascular tissues
PI3K gamma is required for linkage between VLA-4 integrins and the actin cytoskeleton, a critical step for leukocyte recruitment from blood to extravascular tissues
批准号:
184382
负责人:
Rullo Jacob
金额:
$1.7万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2008
资助国家:
加拿大
项目状态:
已结题
起止时间:
2008-10-01 至 2009-06-01
中文摘要
白细胞从血液中募集到组织中是一个重要的过程。白细胞募集是许多炎症性疾病发展的中心,包括多发性硬化症、移植/器官排斥反应和动脉粥样硬化。
英文摘要
The recruitment of white blood cells (leukocytes) from the blood into tissues is an important process. Leukocyte recruitment is central to the development of many inflammatory diseases including multiple sclerosis, transplant/organ rejection and atherosc
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