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Transcriptional control of myelin gene expression and myelination by oligodendrocytes in young adult and aged mice

Transcriptional control of myelin gene expression and myelination by oligodendrocytes in young adult and aged mice
年轻成年和老年小鼠少突胶质细胞对髓磷脂基因表达和髓鞘形成的转录控制
批准号:
277144
负责人:
Nazarali Adil J
金额:
$6.83万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-09-01 至 2014-09-01

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中文摘要
翻译
少突胶质细胞(OLs)是中枢神经系统(CNS)中的一种细胞类型,可以很容易地诱导轴突(从神经细胞延伸出来的长丝)包裹在一种叫做髓磷脂的光滑脂肪蛋白中。髓磷脂隔离轴突,对所有细胞都至关重要
英文摘要
Oligodendrocytes (OLs) are a cell type in the central nervous system (CNS) that can readily be induced to wrap axons (a long filament that extends from nerve cells) in a smooth fatty protein called myelin. Myelin insulates the axon and is critical for all
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Integrated transcriptome analysis of de novo myelination and remyelination efficiency in the aging CNS
  • 批准号:
    366606
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2016
  • 负责人:
    Nazarali Adil J
  • 依托单位:
Transcriptional control of myelin gene expression and myelination by oligodendrocytes in young adult and aged mice
  • 批准号:
    196289
  • 项目类别:
    Operating Grants
  • 资助金额:
    $5.54万
  • 财政年份:
    2009
  • 负责人:
    Nazarali Adil J
  • 依托单位:
海外基金