Charge Stabilization and Electron Transfer in PhotosyntheticReaction Center

将对Rh反应中心复杂功能的结构决定因素进行生物物理和分子生物学相结合的研究。Sphaeroides，目的是通过定点突变的方法，操纵几种活跃在光能转导中的辅因子的功能特性。还在尝试建立RPS的分子遗传学系统。绿色反应中心。同时，将继续对该物种的生物物理特征进行研究。光合作用的主要过程包括光诱导电子从初级电子供体转移到一系列电子受体。这是在称为反应中心的膜结合的色素-蛋白质复合体中完成的。光合作用中参与能量传递的蛋白质为研究蛋白质的生物物理化学及其非凡的活动和行为背后的原理提供了独特的机会。

Combined biophysical and molecular biological studies will be carried out on the structural determinants of the complex functions of reaction centers from Rh. sphaeroides, with the goal of manipulating, by means of site directed mutations, the functional properties of several of the cofactors active in the light energy transduction. Attempts are also being made to establish a molecular genetics system for Rps. Viridis reaction centers. Meanwhile, the biophysical characterization of this species will be continued. The primary process of photosynthesis involves the light-induced transfer of an electron from a primary electron donor to a sequence of electron acceptors. This is accomplished in a membrane bound pigment-protein complex called a reaction center. The proteins involved in energy transduction in photosynthesis provide a unique opportunity for investigating the biophysical chemistry of proteins and the principles behind their remarkable activities and behavior.