Presidential Young Investigator: New Methods of Stereochemical Control

罗伯特·汉森博士获得了合成有机化学项目的总统青年研究员奖，以支持他从实验和理论两方面对立体化学控制发展的研究。这项工作将为合成农业和工业所需的新一代分子提供所需的信息。汉森博士是第一位来自本科院校（RUI）的化学总统青年研究员。研究内容包括：(1)开发用于合成的高立体选择性试剂；(2)开发“试剂选择性”、“底物选择性”和“试剂控制”的直接预测和描述性措施；(3)开发了一种合理的方法来设计对映体的动力学拆分试剂；(4)将“乘法”反应模型扩展到涉及两个以上手性组分的情况；(5)开发和使用对映体富集试剂，使对映体纯底物的反应具有区域选择性；(6)开发立体选择性反应的构象类似物。

Dr. Robert Hanson is being given the Presidential Young Investigator Award from the Synthetic Organic Chemistry Program to support his research into the development of stereochemical control from both experimental and theoretical viewpoints. This work will provide the information required to synthesize the new generation of molecules needed by agriculture and industry. Dr. Hanson is the first chemistry Presidential Young Investigator from an undergraduate institution (RUI). The research will include: (1) the development of highly stereoselectice reagents for synthesis, (2) the development of directly predictive as well as descriptive measures of "reagent selectivity", "substrate selectivity", and "reagent control", (3) the development of a rational approach to the design of reagents for the kinetic resolution of enantiomers, (4) the extension of "multiplicative" reaction models to situations involving more than two chiral components, (5) the development and use of enantiomerically enriched reagents to impart regioselectivity in the reactions of enantiomerically pure substrates, and (6) the development of conformational analogues of stereoselective reactions.