Development of Hybridoma Research Laboratory

该提案请求国家科学基金会提供援助，在德克萨斯大学圣安东尼奥分校(UTSA)建立一个多用户杂交瘤研究实验室。该实验室将：(1)通过提供目前尚不存在的昂贵、最先进的设备，促进将单抗(MAb)技术应用于正在进行和计划中的研究计划，从而增强和加强生命科学教师的研究能力；(2)增进和加强少数族裔本科生和研究生的研究经验，促进获得智力和身体技能，以便在生物学领域具有竞争力，该领域的地位正在迅速达到科学界要求的背景；以及(3)促进UTSA与其他在生物科学领域有大量少数民族入学的地区性学术机构之间的研究互动。此外，增强的研究经验预计将有助于增加少数族裔学生进入生物科学领域的职业。最初，9名研究人员和他们的学生提议利用杂交瘤研究实验室促进单抗技术在生理学、分子细胞生物学、遗传学、生物化学和神经生物学等正在进行的研究项目中的应用。这些研究项目每年将影响14名本科生和7名研究生。

This proposal requests assistance from the National Science Foundation to establish a multiuser Hybridoma Research Laboratory at The University of Texas at San Antonio (UTSA). The laboratory will: (1) enhance and strengthen the research capabilities of life science faculty by providing expensive, state-of-the-art equipment, not presently available, to facilitate the application of monoclonal antibody (MAb) technology to ongoing and planned research programs; (2) enhance and strengthen research experiences for minority undergraduate and graduate students by facilitating the acquisition of intellectual and physical skills to become competitive in an area of biology which is rapidly achieving status as required background by the scientific community; and (3) foster research interactions between UTSA and other regional academic institutions with large minority enrollments in the biological sciences. Furthermore, the enhanced research experiences are expected to contribute to increased entry of minority students into careers in the biosciences. Initially nine investigators and their students propose to utilize the Hybridoma Research Laboratory to facilitate the application of MAb technology to ongoing research programs in physiology, molecular cell biology, genetics, biochemistry and neurobiology. These research programs will impact 14 undergraduate and 7 graduate minority students per year.//