Axonal Pathfinding in the Developing Avian Retina

这些研究将阐明参与的分子和机制 轴突的定向生长 单克隆和多克隆 将产生抗体并用于识别抗原 在鸡的神经视网膜中表达， 视网膜轴突生长和方向性。 移植 将进行体内和器官培养实验， 研究向化性机制在定向中的作用， 视网膜神经节轴突 这些研究承诺提供 参与的分子机制的基本信息 轴突生长在发展中，以及在再生。

These studies will elucidate molecules and mechanisms involved in directional growth of axons. Monoclonal and polyclonal antibodies will be raised and employed to identify antigens expressed in the chick neural retina that play a functional role in retinal axonal growth and directionality. Transplantation experiments in vivo and in organ culture will be performed to study the role of chemotropic mechanisms in orientation of retinal ganglion axons. These studies promise to provide fundamental information on the molecular mechanisms involved in axonal growth in development, as well as in regeneration.