Mitochondrial vulnerability to stress: An early maladaptive response in adverse ventricular remodelling.
Mitochondrial vulnerability to stress: An early maladaptive response in adverse ventricular remodelling.
批准号:
190999
负责人:
Burelle Yan
金额:
$34.84万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2009
资助国家:
加拿大
项目状态:
已结题
起止时间:
2009-09-01 至 2013-09-01
中文摘要
尽管已知心脏肥厚和心力衰竭之间存在关联,但从代偿性肥厚到心力衰竭的转变机制仍然知之甚少。一些证据表明,在衰竭阶段,线粒体(线粒体
英文摘要
Despite the known association between cardiac hypertrophy and heart failure the mechanisms involved in the transition from compensated hypertrophy to failure remain poorly understood. Several evidences indicate that in the failing stage mitochondria (the
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