Investigating the metabolic drivers of hyperinflammation during viral infection
Investigating the metabolic drivers of hyperinflammation during viral infection
批准号:
462594
负责人:
Ashkar Ali A
金额:
$76.07万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2022
资助国家:
加拿大
项目状态:
未结题
起止时间:
2022-03-01 至 2027-03-01
中文摘要
成功的宿主防御需要严格控制炎症,以建立有效的免疫反应,同时限制对宿主的损害。这种炎症控制的丧失可导致“细胞因子风暴”——一种病理性失调的免疫反应特征
英文摘要
Successful host defense requires tight control of inflammation to mount an effective immune response while limiting damage to the host. Loss of such inflammatory control can result in "cytokine storm" - a pathological dysregulated immune response characte
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Canada Research Chair - Tier 1
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批准号:453859
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项目类别:
-
资助金额:$101.99万
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财政年份:2020
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负责人:Ashkar Ali A
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依托单位:
Utilizing chimeric antigen receptors to direct autologous NK cell cytotoxicity to breast cancer
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批准号:380931
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项目类别:Operating Grants
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资助金额:$68.31万
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财政年份:2018
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负责人:Ashkar Ali A
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依托单位:
Investigating the regulatory functions of type I IFNs and NK cells during mucosal viral infections
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批准号:371828
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项目类别:Operating Grants
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资助金额:$59.56万
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财政年份:2017
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负责人:Ashkar Ali A
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依托单位:
CRC Tier 1
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批准号:314117
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项目类别:
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资助金额:$101.99万
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财政年份:2013
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负责人:Ashkar Ali A
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依托单位:
Role of NK cells in innate defense against mucosal viral infections
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批准号:253595
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项目类别:Operating Grants
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资助金额:$55.76万
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财政年份:2012
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负责人:Ashkar Ali A
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依托单位: