Directed Reactions of Indenyl-Metal Complexes

9315999傅园慧该奖项是傅园慧博士化学博士后研究奖学金的起始拨款增量。研究的重点是使用吲哚金属络合物来指导催化过程。具体地说，金属结合吲哚配体的环滑移将被用来打开金属体系上的配位位置，从而为催化提供必要的配位不饱和反应中间体。这一机制的一个重要特征是，由于过渡态的高度组织化，增强了对反应的立体控制。初步研究将探索吲哚基铑配合物在催化烯烃氢化、硼氢化和氢甲酰化中的应用。这项关于定向催化反应的研究将提供对反应活性的基本见解以及合成有机化学的新方法。***

9315999 Fu This award is the starter grant increment of Dr. Fu's Postdoctoral Research Fellowships in Chemistry award. The focus of the research deals with the use of indenyl-metal complexes to direct catalytic processes. Specifically, ring slippage of the metal-bound indenyl ligand will be exploited to open up coordination sites on metal systems to provide the necessary coordinatively-unsaturated reactive intermediates for catalysis. An important feature of this mechanism is enhanced stereocontrol of the reaction due to the high level of organization in the transition state. Initial studies will explore indenylrhodium complexes in catalytic olefin hydrogenation, hydroboration and hydroformylation. %%% This research on directed catalytic reactions will provide fundamental insights into reactivity as well as new methods for synthetic organic chemistry. ***