The roles of the core autophagy protein ATG4B in chronic myeloid leukemia acquired drug resistance and its therapeutic implications
The roles of the core autophagy protein ATG4B in chronic myeloid leukemia acquired drug resistance and its therapeutic implications
批准号:
365540
负责人:
Porter Vanessa L
金额:
$7.65万
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-10-01 至 2019-10-01
中文摘要
目前慢性髓性白血病(CML)的治疗依赖于抑制剂,如甲磺酸伊马替尼(IM)和更新的迭代酪氨酸激酶抑制剂(TKIs)来靶向融合蛋白BCR-ABL1,这是CML作为一种疾病的特征。然而,bcr - abl1
英文摘要
Current treatment for chronic myeloid leukemia (CML) relies on inhibitors such as Imatinib Mesylate (IM) and newer iteration tyrosine kinase inhibitors (TKIs) to target the fusion protein, BCR-ABL1, which characterizes CML as a disease. However, BCR-ABL1
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会议论文
Targeting autophagy in chronic myeloid leukemia through inhibition of the core autophagy protein ATG4B
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批准号:368471
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项目类别:
-
资助金额:$0.07万
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财政年份:2017
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负责人:Porter Vanessa L
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依托单位:
海外基金