Mechanisms of driver mutation cooperativity in precursor B cell acute lymphoblastic leukemia
Mechanisms of driver mutation cooperativity in precursor B cell acute lymphoblastic leukemia
批准号:
408514
负责人:
DeKoter Rodney P
金额:
$67.71万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-09-01 至 2024-09-01
中文摘要
B细胞急性淋巴细胞性白血病是一种主要发生在儿童中的血癌。B细胞白血病是由血细胞DNA罕见的突变引起的。我们实验室利用转基因小鼠建立了B细胞白血病的模型
英文摘要
B cell acute lymphoblastic leukemia is type of blood cancer that occurs primarily in children. B cell leukemia is caused by rare mutations in the DNA of blood cells. Our laboratory models the development of B cell leukemia using genetically modified mice
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