Functional roles of glycogen synthase kinase-3 in cellular regulation and cancer
Functional roles of glycogen synthase kinase-3 in cellular regulation and cancer
批准号:
189383
负责人:
Woodgett James (Jim) R
金额:
$73.14万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2009
资助国家:
加拿大
项目状态:
已结题
起止时间:
2009-09-01 至 2014-09-01
中文摘要
我们一直在研究一对蛋白质,它们在组织中具有一种不寻常的功能,通过为通常促进生长和采用特定细胞命运的信号提供节流,从而起到看门人的作用。这些蛋白的生长抑制作用是循环的
英文摘要
We have been studying a pair of proteins that have an unusual function as gate-keepers in tissues by providing a throttle to signals that normally promote growth and adoption of particular cell fates. The growth inhibitory effects of these proteins is cle
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Genetic analysis of signal transduction pathways involved in human diseases.
-
批准号:312975
-
项目类别:Operating Grants
-
资助金额:$187.39万
-
财政年份:2014
-
负责人:Woodgett James (Jim) R
-
依托单位:
Wnt signaling: biomarker and target evaluation in Alzheimer's disease
-
批准号:283714
-
项目类别:Operating Grants
-
资助金额:$17.54万
-
财政年份:2013
-
负责人:Woodgett James (Jim) R
-
依托单位:
Investigation of the roles of GSK-3 isoforms in mediating Abeta, tau and insulin related Alzheimer-like synaptic, cholinergic impairments
-
批准号:264464
-
项目类别:Operating Grants
-
资助金额:$72.85万
-
财政年份:2012
-
负责人:Woodgett James (Jim) R
-
依托单位:
2012 Synapse Mentorship Award (Research Group) The Samuel lunenfeld Research Institute (SLRI)
-
批准号:257092
-
项目类别:
-
资助金额:$0.73万
-
财政年份:2012
-
负责人:Woodgett James (Jim) R
-
依托单位:
海外基金