Sex-specific impact of the manipulation of methionine cycle on T cell activation and gut microbiome in neuroinflammation
Sex-specific impact of the manipulation of methionine cycle on T cell activation and gut microbiome in neuroinflammation
批准号:
449594
负责人:
Millette Florence
金额:
$1.27万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2020
资助国家:
加拿大
项目状态:
已结题
起止时间:
2020-12-01 至 2021-12-01
中文摘要
多发性硬化症(MS)是一种自身免疫性疾病,其特征在于在免疫细胞(尤其是促炎性T细胞)异常活化的背景下脑和脊髓中的病变。女性受MS的影响是男性的3倍。的病因
英文摘要
Multiple sclerosis (MS) is an autoimmune disease characterized by lesions in the brain and spinal cord in a context of aberrant activation of immune cells, especially pro-inflammatory T cells. Women are 3 times more affected by MS than men. The etiology o
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