Milk Protein Origins

9509551盖特西这项研究涉及牛奶酪蛋白基因的进化。在这个项目中，将收集和解释与营养牛奶胶束的稳定成分k-酪蛋白的分子起源有关的DNA序列数据。将讨论两个主要问题：1)酪蛋白基因是否有助于重建哺乳动物之间的进化关系；2)酪蛋白从何而来？通过对来自k-酪蛋白、g-纤维蛋白原和b-酪蛋白(一种对钙敏感的酪蛋白)的DNA序列进行系统发育分析，可以从分子进化的角度探索一项重大的生理突破。***

9509551 Gatesy This research involves the evolution of milk casein genes. In this project, DNA sequence data bearing on the molecular origin of k-casein, a stabilizing component of the nutritional milk micelle will be collected and interpreted. Two major questions will be addressed: 1) Are casein genes useful for the reconstruction of evolutionary relationships among mammals, and 2) Where did caseins come from?. %%% Through phylogenetic analysis of DNA sequences from k-casein, g-fibrinogen, and b-casein (a calcium sensitive casein), a major physiological breakthrough can be explored from a molecular evolutionary perspective. ***