CAREER: Polysaccharide Composite Materials for Engineering of Vascular Tissue

马修：这个职业发展计划包括研究和教育活动。该研究的目的是开发细胞种子管状假体，使其基质中的平滑肌和管腔表面的内皮细胞增殖。基质的主要化学成分将是糖胺聚糖，一种来自结缔组织的生物活性多糖。研究将集中在表征假体的物理化学特性，评估血管细胞在这些材料上的生长，以及开发模拟体外系统进行全面评估。教育计划的目标是参与课程开发，重点是基于问题的学习和小组学习，并促进少数民族学生的招募、保留和指导活动。＊＊＊

9624151 Matthew This career development plan contains both research and education activities. The objective of the research is the development of cell-seeded tubular prostheses that will allow for the proliferation of smooth muscle in its matrix and endothelial cells on its luminal surface. The primary chemical constituent of the matrix will be glycosamioglycans, a biologically active polysaccharide from connective tissues. The research will focus on characterizing the physicochemical properties of the prostheses, evaluation of the growth of vascular cells on these materials, and the development of a simulated in vitro system for overall evaluation. The goal of the education plan is to engage in curriculum development with an emphasis on Problem-Based Learning and Group Learning, and to foster minority student recruitment, retention and mentoring activities. ***