Acquisition of Departmental Mass Spectrometers

9632905得克萨斯大学奥斯汀哈克特大学该奖项来自化学研究仪器和设施计划和学术研究基础设施计划，将帮助得克萨斯大学奥斯汀大学化学与生物化学系获得质谱仪。该设备将加强以下领域的研究：(1)特殊环境中的光致电子转移(2)RNA结构和RNA-蛋白质相互作用的结构基础(3)pi束、具有非共价高阶结构的大分子合成分子的分子量和结构信息(4)分子量测量和几千Da抗病毒剂的合成载体。(5)氢键驱动的小分子间分子识别；(6)新生多肽。质谱仪(MS)是一种用于探测大量有机、生物有机和有机金属分子的内部结构细节和获得其分子组成的技术。电喷雾技术的加入将MS的范围扩展到蛋白质和核酸的相对分子质量，远远超过了任何其他技术。电喷雾电离与高分辨率相结合的使用提供了质谱学中可用的最新技术。它为化学家提供了表征化合物的最强大的工具之一。在质谱学中获得这种能力对于开展许多化学领域的前沿研究是至关重要的。

9632905 Hackert University of Texas Austin This award from the Chemistry Research Instrumentation and Facilities (CRIF) Program and the Academic Research Infrastructure (ARI) Program will assist the Department of Chemistry & Biochemistry at the University of Texas Austin acquire a Mass Spectrometer. This equipment will enhance research in a number of areas including the following: (1) photo induced electron transfer in unusual environments (2) RNA structure and the structural basis of RNA-protein interactions (3) molecular weight and structural information of pi-beams, large synthetic molcules with noncovalent higher order structures (4) mass measurements of expanded porphyrins and synthetic carriers for antiviral agents with molecular weights of several thousand Da. (5) hydrogen-bond-driven molecular recognition between small molecules, and (6) nascent peptides. Mass spectrometry (MS) is a technique used to probe intimate structural details and to obtain the molecular compositions of a vast array of organic,bioorganic, and organometallic molecules. The addition of the technique of electrospray extends the range of MS to proteins and nucleic acid molecular weights far beyond any other technique. The use of electrospray ionization in combination with high resolution provides the latest techniques available in mass spectrometry. It affords the chemist one of the most powerful tools available for the characterization of compounds. The acquisition of this capability in mass spectrometry is essential for the prosecution of frontier research in many fields of chemistry.