1997 International Symposium: "The Ribosome-Its Nucleolar Synthesis and Structure" to be held in Noordwijkerhout, The Netherlands, August 16-20, 1997.

9725106 Pikaard美国国家科学基金会正在资助研究生和博士后研究员前往美国参加题为“核糖体：其核仁合成和结构”的国际研讨会。这次会议将于1997年8月16日至20日在荷兰诺德韦克豪特举行。 这次会议将是第四次在冷泉港举行的会议（1988年，1991年，1994年）。 核糖体生物合成的研究包括生物化学、生物物理学、遗传学、细胞生物学、发育生物学和生理学等分支学科。 许多原核生物和真核生物都是模型系统，包括大肠杆菌。大肠杆菌、酵母、阿米巴、锥虫、植物、果蝇和哺乳动物。 核糖体合成会议汇集了来自世界各地的研究实验室，所有这些都由一个单一的主题统一起来。 为这次会议聚集的科学家的专业知识的广度促进了跨学科的互动和新的见解的发展。 这次会议向学生介绍了他们的研究数字的更大背景，并经常首次向他们介绍与自己不同的学科的复杂研究。 核糖体由多个rRNA和大约80种蛋白质组成，其合成和组装必须精确协调。 在真核生物中，所有三种核RNA聚合酶都需要表达必需的基因。 rRNA和核糖体蛋白的细胞运输也是细胞的主要后勤问题。 在原核生物和真核生物中，控制发生在多个步骤，包括转录起始、RNA加工、RNA周转、转录后修饰、转录终止和蛋白质周转。 将蛋白质和rRNA组装成功能性核糖体也是吸引结构生物学家进入这一领域的一个问题。 为了鼓励美国学生在他们的教育中寻求国际经验，会议将提供一种机制，让对国外博士后经验感兴趣的学生可以与实验室主任（主要在欧洲）会面，他们预计他们的实验室会有空缺。 通过这种方式，组织者希望为美国学生提供国际研究培训和经验，这与美国国家科学基金会的许多教育使命之一是一致的。 核糖体负责所有生物体中的蛋白质合成。 专门研究这些基本细胞“机器”的科学家将从世界各地聚集在荷兰参加题为“核糖体：其核仁合成和结构”的会议。“会议为拥有广泛专业知识的科学家提供了分享这一领域信息和见解的机会。 国家科学基金会提供的资金将使美国研究生和博士后研究员能够出席会议，并为他们提供安排国际合作的机会。 ***

9725106 Pikaard The National Science Foundation is providing funding for the travel of graduate students and postdoctoral fellows in the United States to attend an international symposium entitled "The Ribosome: Its Nucleolar Synthesis and Structure." This meeting will be held in Noordwijkerhout, the Netherlands, August 16-20, 1997. This conference will be the fourth incarnation of a meeting that has previously been held at Cold Spring Harbor (1988, 1991, 1994). The study of ribosome biosynthesis encompasses the sub-disciplines of biochemistry, biophysics, genetics, cell biology, developmental biology and physiology. Numerous prokaryotic and eukaryotic species are model systems including E. coli, yeast, Acanthamoeba, trypanosomes, plants, Drosophila, and mammals. Ribosome synthesis meetings bring together research laboratories from around the world, all unified by a single topic. The breadth of expertise of the scientists assembled for this meeting facilitates interdisciplinary interactions and the development of new insights. This meeting presents students with the larger context in which their research figures and often introduces them for the first time to sophisticated research in disciplines distinct from their own. Ribosomes are composed of multiple rRNAs and approximately 80 proteins whose synthesis and assembly must be precisely coordinated. In eukaryotes, all three nuclear RNA polymerases are required to express the requisite genes. Cellular trafficking of rRNAs and ribosomal proteins is also a major logistical problem for the cell. Control in both prokaryotes and eukaryotes occurs at multiple steps including transcription initiation, RNA processing, RNA turnover, post-transcriptional modification, transcription termination and protein turnover. Assembly of the proteins and rRNAs into a functional ribosome is a problem that also attracts structural biologists to this field. To encourage US students to seek out international experience in their education, the meeting will provide a mechanism by which students interested in postdoctoral experience abroad can meet with laboratory directors (mostly in Europe) who anticipate openings in their laboratories. In this way, the organizers hope to facilitate international research training and experience for American students, consistent with one of the many educational missions of the National Science Foundation. Ribosomes are responsible for protein synthesis in all organisms. Scientists specializing in the study of these essential cellular "machines" will gather from all over the world in the Netherlands for the meeting entitled "The Ribosome: Its Nucleolar Synthesis and Structure." The meeting provides scientists having a wide range of expertise the opportunity to share information and insights into this field. Funding from the National Science Foundation will enable United States graduate students and postdoctoral fellows to attend the meeting and will provide them with the opportunity to arrange international collaborations. ***