U.S.-Singapore Cooperative Research: Database Integration in the Drosophila Developmental Pathway

9725507钟这是一个为期36个月的奖项，由健康科学统一服务大学的钟素云博士和维斯塔尔研究所的Subramanian Subbiah博士与新加坡国立大学的王林顺博士合作提出。钟素云博士和Subramanian Subbiah博士申请经费用于旅行、通讯、实验室用品和计算机时间，以使用从果蝇眼收集的遗传数据作为模型，进行一项涉及数据集成和信息合成系统的试点实验。这项研究的目的是开发一个数据库查询和集成工具来处理复杂的生物学问题。钟博士的专长是同源异型盒基因调控。苏比亚博士接受过蛋白质结构和功能方面的培训。他们的新加坡同行科学家王林顺博士是一名系统科学家，在生物信息学方面拥有深厚的背景。他们的专业领域对于实现项目目标是相辅相成的。这项研究解决了一个非常重要的基本问题，即整合来自不同来源的生物信息，并可能对生物信息学产生重大影响。这是一个尖端项目，将使用美国和新加坡之间的甚快骨干网络系统(VBNS)连接。该项目由新加坡科技局和国家科学基金会共同支持。

9725507 Chung This is a 36 month award proposed by Drs. Su-Yun Chung, Uniformed Service University of the Health Science, and Subramanian Subbiah, Wistar Institute, collaborating with Dr. Limsoon Wong, National University of Singapore. Drs. Su- Yun Chung and Subramanian Subbiah request funds for travel, communications, laboratory supplies, and computer time to carry out a pilot experiment involving a data integration and information synthesis system using the genetic data collected from the fruit fly eye as a model. The purpose of this study is to develop a database query and integration tool to handle complex biological problems. Dr. Chung's expertise is in the area of homeobox gene regulation. Dr. Subbiah is trained in protein structure and function. Their Singapore counterpart scientist, Dr. Limsoon Wong, is a system scientist with a strong background in bioinformatics. Their areas of expertise are complimentary for meeting the project goals. This study addresses a very important fundamental question of integrating biological information from disparate sources and could have a significant impact on bioinformatics. This is a cutting edge project, which will use the very Fast Backbone Network System (vBNS) connection between the U.S. and Singapore. The project is jointly supported by the Singapore Science and Technology Board and the NSF.