I. Convergent Double Annulation Route to Highly Substituted and Oxidized Bicyclo{4.n.0}alkanes. II. Engaging Students as Participants in their Own Education.

本研究的重点是开发一种双环路 具有多个官能团的双环（4.n.0）烷烃的制备策略 功能和替代。 该方法的实用性，其中采用 一个串联的迈克尔，迪克曼序列，将展示的 制备了许多有趣的多萜类化合物。 的重点 教育活动是关于课程开发， 基于网络的互动作业和论文作业。 与此 教师早期发展（职业生涯）奖，有机和大分子 化学计划是支持研究和教育活动 罗伯特B博士的格罗斯曼在化学系在 肯塔基州大学。 格罗斯曼教授将把他的研究重点 努力开发合成方法， 具有有趣的生物学特性的有机化合物。 的 该奖项的教育部分将强调课程开发， 本科有机化学

The focus of this research is the development of a double annulation strategy for the preparation of bicyclo(4.n.0)alkanes with multiple functionality and substitution. The utility of the method, which employs a tandem Michael, Dieckmann sequence, will be showcased by the preparation of a number of interesting polyterpenoids. The focus of the educational activities is on course development featuring the use of web-based, interactive homework and essay assignments. With this Faculty Early Development (CAREER) award, the Organic and Macromolecular Chemistry Program is supporting the research and educational activities of Dr. Robert B. Grossman of the Department of Chemistry at the University of Kentucky. Professor Grossman will focus his research efforts on developing synthetic methodology useful in the preparation of organic compounds having interesting biological properties. The educational component of the award will stress course development in undergraduate organic chemistry.