Cytochrome c: A Biochemistry Laboratory

化学系正在开设一门新的生物化学实验课程，并准备了实验设备。该系以前没有开设过生物化学实验课程，在大学的其他地方也没有开设过类似的课程。因此，新课程填补了该系课程的空白。本课程每周授课1小时，实验6小时，共3学分。本课程背后的概念是避免用各种各样的实验室实验来填满时间。相反，该课程侧重于生化研究的过程。实验室完全处理细胞色素c，模拟现实世界研究项目的经验。这个实验室是围绕团队学习建立的。学生团队分离细胞色素c，通过各种生化和生物无机方法对其进行表征，确定其功能，并修改蛋白质以产生化学核酸酶。这个过程向他们介绍了核酸的生物有机化学。学生们已经做好了充分的准备，可以通过进行本科研究和学习额外的生物化学课程来继续他们的本科生物化学教育。通过让学生接触到研究问题的兴奋，本课程支持他们在生物化学研究领域追求职业的兴趣。＊

The Department of Chemistry is developing a new biochemistry laboratory course and obtaining equipment for this laboratory. The Department has not previously offered a biochemistry laboratory course, and no comparable course has been offered elsewhere at the university. Thus, the new course fills a void in the department's curricula. The course consists of 1 hour of lecture and 6 hours of laboratory a week for 3 credits. The concept behind this course is to avoid filling the time with a collection of miscellaneous laboratory experiments. Instead, the course focuses on the process of biochemical research. The laboratory deals entirely with cytochrome c, simulating the experience of a real-world research project. The laboratory is being built around team learning. Teams of students isolate cytochrome c, characterize it by a variety of biochemical and bioinorganic methods, determine its function, and modify the protein to produce a chemical nuclease. This process introduces them to the bio-organic chemistry of nucleic acids. Students are being well prepared to continue their undergraduate education in biochemistry by performing undergraduate research and taking additional biochemistry courses. By exposing the students to the excitement of research problems, the course is supporting their interests in pursuing careers in biochemical research. *