Support for Second Metabolic Engineering Conference, October 25-30, 1998, Baveria, Germany

9812879 Sinskey本次会议的目的是提供一个代谢工程的目标和原则的共识定义。 第一次强调代谢工程的工程基金会会议题为“重组DNA生物技术：关注代谢工程”，于1996年10月6日至11日在马萨诸塞州丹弗斯举行。 一个由化学工程师、计算科学家、分子生物学家和生物化学家组成的国际小组举行会议，讨论有关代谢工程领域出现的一些重要问题。 代表工业界、学术界和政府的国际团体踊跃参加了会议。 组委会建议两年后在欧洲举行第二次会议，题为代谢工程II（ME II）。 第二次世界气象大会定于1998年10月25日至30日在德国巴伐利亚州的施洛斯埃尔毛宫举行。 ME II的一个关键目标是试图澄清代谢工程与其他已建立领域的主要差异，并提供这一新研究领域所探索的独特视角。 这里的一个重要方面是了解通过代谢途径控制通量的因素和机制。 具体而言，已计划就下列专题举行会议：（1）实验和计算工具，（2）用于药物、燃料和化学品生产的代谢工程，（3）代谢工程在材料合成中的应用，（4）植物系统中的代谢工程，（5）代谢工程在蛋白质生产中的作用，（6）通过代谢工程进行菌株改良的进化策略，（7）医学应用和基因治疗，（8）通过调控基因进行更高水平的代谢工程，（9）代谢工程在环境问题中的应用，以及（10）未来方向。***

9812879 Sinskey The objective of this conference is to provide a consensus definition of the goals and principles of Metabolic Engineering. The first Engineering Foundation conference that emphasize Metabolic Engineering was entitled "Recombinant DNA Biotechnology: Focus on Metabolic Engineering" and was held from October 6-11, 1996, in Danvers, MA. An international group of chemical engineers, computational scientists, molecular biologists and biochemists met to address a number of important issues regarding the emergence of the field of metabolic engineering. The conference was very well attended by an international group representing industry, academia and government. The organizing committee recommended that a second conference entitled Metabolic Engineering II (ME II) be held in Europe two years later. ME II is scheduled for October 25-30, 1998, at Schloss Elmau/Oberbayern (Bavaria), Germany. A key objective of ME II will be an attempt to clarify the main differences of metabolic engineering from other established fields and also to provide the unique perspectives which are explored by this new area of research. An important aspect here is understanding the factors and mechanisms contributing to the control of flux through metabolic pathways. Specifically, sessions on the following topics have been planed: (1) experimental and computational tools, (2) metabolic engineering for production of pharmaceuticals, fuels and chemicals, (3) use of metabolic engineering in the synthesis of materials, (4) metabolic engineering in plant systems, (5) role of metabolic engineering in the production of proteins, (6) evolutionary strategies for strain improvement via metabolic engineering, (7) medical applications and gene therapy, (8) higher-level metabolic engineering through regulatory genes, (9) use of metabolic engineering for environmental problems, and (10) future directions. ***