Postdoctoral Research Fellowship in Biological Informatics for FY 1999

这一行动资助了NSF 1999年的生物信息学博士后研究奖学金。这项研究和培训计划是在真核遗传学领域，名为“表征母体基因对后代早期发育特征表达的影响的方法”。母亲体内表达的基因通常会影响子代的特征表达。这些所谓的母性效应是普遍存在的，但传统上在遗传结构研究(例如，QTL分析)中被忽视。正在开发将母体效应纳入QTL分析的方法，并将这些方法应用于检查小鼠发育的遗传学。

This action funds an NSF Postdoctoral Research Fellowship in Biological Informatics for 1999.The research and training plan is in the area of eukaryotic genetics and is entitled "Methods for characterizing the effect of maternal genes on the expression of early developmental traits in offspring."Genes expressed in mothers often influence the expression of traits in their offspring. These so-called maternal effects are ubiquitous but have traditionally been ignored in studies of genetic architecture (e.g., QTL analysis). Methods are being developed to incorporate maternal effects into QTL analyses and apply these methods to examine the genetics of development in the mouse.