Research Experience for Undergraduates in Molecular Biology and Genetics

摘要 伊夫·布伦 DBI#9987835在过去的两年里，在印第安纳州布卢明顿大学的资助下，MBG项目的成员们通过允许他们参与分子生物学和遗传学前沿的研究，将20名大部分来自小型学院的本科生引入了迷人的科学研究世界。 一个REU网站赠款将允许一个非常成功的本科研究计划的延续，使学生主要受益于传统上在研究中代表性不足的群体和来自区域本科院校的学生。 10名学生将在分子生物学和遗传学实验室进行研究，研究问题包括基因表达的调控、细胞分化和发育的机制、植物中的寄主-寄生虫相互作用和抗病性、基因进化、信号转导、DNA修复、病毒感染和复制。该计划旨在培养参与者的技术和智力能力。 哲学是，一个人学会如何做研究，但这只发生在适当的指导下。 该计划将通过让学生在密切监督下参与研究项目来强调研究的“做R”方面。 学生将通过与导师的互动以及科学写作和研究伦理的课程来了解科学调查的不同阶段和方面。 学生还将接触到在其他主机实验室进行的研究期间，由教师导师给予每周午餐时间研讨会。

ABSTRACT Yves V. Brun DBI# 9987835In the last two years, with funding from Indiana University-Bloomington, the members of the MBG Program have introduced 20 undergraduate students, mostly from small colleges, to the fascinating world of scientff ic research by allowing them to participate in research at the frontiers of molecular biology and genetics. An REU Site Grant will allow the to continuation of a very successful Undergraduate Research Program to benefit students mainly from groups traditionally underrepresented in research and students from regional undergraduate institutions. Ten students will conduct research in laboratories that use molecular biology and genetic techniques to study problems including the regulation of gene expression, the mechanisms of cell differentiation and development, host-parasite interaction and disease resistance in plants, gene evolution, signal transduction, DNA repair, and virus infection and replication.This program is designed to develop both the technical and the intellectual abilities of the participants. The philosophy is that one learns how to do research by doing it but that this only occurs under the appropriate guidance. The program will emphasize the "doing R" aspect of research by involving the students in a research project under close supervision. Students will learn about the different stages and aspects of scientific investigation by interaction with their mentors and in sessions on scientific writing and research ethics. Students will also be exposed to the research conducted in the other host laboratories during weekly lunchtime seminars given by faculty mentors.